Letrozole can sometimes cause headache, nausea (feeling sick) and vomiting (being sick). While many people find that these problems will improve over time, talk to a member of your specialist team or as they may be able to offer suggestions that will help. Simple pain relief such as paracetamol may help with headache, and anti-sickness medication can be prescribed if you have nausea or vomiting. Taking your letrozole with or after food can help reduce nausea.
Below is from a Letrozole Patient Information Leaflet:
Common (may affect up to 1 in 10 people):
- increase in or loss of appetite,
- sad mood (depression),
- headache, dizziness,
- raised blood pressure,
- nausea, vomiting, indigestion, constipation, diarrhoea, stomach-ache,
- hair loss and skin rash, dry skin,
- muscle pain, bone pain, thinning or wasting of your bones (osteoporosis), leading to bone fractures in some cases (see also section 2),
- vaginal bleeding,
- weight increase,
- swelling of arms, hands, feet, ankles (peripheral oedema).
Anyway, whether it is the letrozole or not, maybe someone should be investigating the cause if it is a persistant issue.
Best wishes to you x