cancel
Showing results for 
Search instead for 
Did you mean: 

Letrozole before or after rads

12 REPLIES 12
Member

Re: Letrozole before or after rads

Thanks northerngal for your lovely positive reply. I guess we are all affected differently. Tip taken onboard re lots of moisturiser.
Hugs back xx
Member

Re: Letrozole before or after rads

Hi Bellas Mum

 

Best not to compare yourself to anyone else's treatment as we are all different. I too was told to start Letrozole before rads. Like you clear nodes and margins. Started Letrozole in Feb and rads started the end of March so was already 6 weeks into Letrozole before I started  rads. After reading some of the posts regarding Letrozole I was really scared but the only SE I have are hot flushes and this is manageable. I count myself lucky as I know some ladies have a number of SE. The only SE I had with rads was the tiredness and I put this down to the daily back and forth. I'm 7 weeks post rads and my skin is absolutely fine and I put this down to lots of moisturiser.  I'm pretty much back to a new normal and started back at work this week after 5 months away. It is a difficult time but try to be positive, you will get through this.

 

 Sending hugs xx

Member

Re: Letrozole before or after rads

Thanks Sunflower
Am so confused by all this. There doesn't seem to be any set guidance. Have taken 3 days worth now but reading what others have written it makes sense. I had very clear margins and no node involvement so perhaps that's why they said to start. BCN has said that as I am not having chemotherapy to take them! It really is a minefield. Start my rads on the 27th. Got the letter yesterday so will be very soon. CT next week too.

Good luck with the rest of your treatment x
Community Champion

Re: Letrozole before or after rads

Hi

I started taking it straight after chemo and before rads. Any side effects that you may get from the letrozole, do not start straight away......takes about 6 weeks to kick in. No harm in starting it now. 

Sue xx

Member

Re: Letrozole before or after rads

Thanks Ann. Yes you are right with reporting bias. Suppose when we find ourselves with a diagnosis, the treatment, surgery etc the anxiety levels are raised. x
Community Champion

Re: Letrozole before or after rads

Yes Bella, I remember feeling anxious about it all when reading experiences here, but understandably, those having issues will tend to post, not those who are ok, so there is a bit of a reporting bias.
ann x
Member

Re: Letrozole before or after rads

Thanks Andi

Yes that does help. Reading about some of the horrible side effects some ladies are having is really scary. Thank you again x
Highlighted
Member

Re: Letrozole before or after rads

Hi Bellas mum

I asked the same question myself on the forum a couple of months ago.
Like you I was given a Letrozole prescription by my oncologist but with no clear instructions when to start. My radiotherapy appts did not start for several weeks after.

The consensus was that the instructions on this can vary.

I telephoned the oncology department and was told to start immediately and this was 5 weeks before rads.

I had very little side effects from Letrozole in the first few weeks so really don't worry too much about the radiotherapy.

In fairness my side effects from the meds so far are all manageable and I'm trying to stay positive long term in the hope that they settle down.

Hope this helps xx
Member

Re: Letrozole before or after rads

Thanks ladies. Can see why they say start after now. Makes sense I think. Just no instruction given at all. Just that I would need Letrozole. Just spoke to BCN  and she said as I was not having chemo then to start. Not looking forward to rads as it is along with the side effects of the tablets 

Community Champion

Re: Letrozole before or after rads

Hm - that's weird - it comes up as page not found. Try Googling the title of the article - 

Concurrent or Sequential Hormonal and Radiation Therapy in Breast Cancer: A Literature Review

Basically I guess you'd need to look at any studies that compare concurrent or sequential.

Community Champion

Re: Letrozole before or after rads

Hi Bellas Mum

I think the jury is still out on this one but having also been given my hormone prescription prior to rads last year  I did a bit of research and came up with this scholarly article

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4659580/  which made me decide to start taking it on the evening of the last day or rads. I believe it is something to do with zapping the cells when they are active, as Ann-m suggests.

It also meant that if there were any side-effects from either treatment they wouldn't be happening at the same time.

You may want to check with your oncologist to be sure, but when i confessed to mine after the event that I'd started them after rads he didn't seem too concerned. A lot of people on here say they have been given the choice anyway. I hope the next stage goes well for you. XX

Community Champion

Re: Letrozole before or after rads

Hi Bellas Mum,
Advice on this does vary. I’m on tamoxifen & was told to start the day after rads finished. I think is was to do with not putting any rogue cells left behind to sleep, so that they were zapped by rads!
...but others are told to start immediately.
Hopefully someone will be along with the answer, otherwise it might be an idea to check with your team or the nurses here.
ann x
Member

Letrozole before or after rads

Hi all

 

saw Oncologist yesterday and he has given me a prescription for Letrozole.  No instructions either! Do I take it now or after my radiotherapy????