Member
Posts: 1
Registered: ‎08-12-2017

Re: Leg Cramps and Tamoxifen

I’ve been on tamoxifen for 6 months now and thought I’d got off quite lightly with regard to side effects but suddenly am now suffering from really horrendous calf and toe cramps during the night - to the point that my legs are still sore the next day!  Thank you to everyone contributing to this thread - hopefully some combination of the suggestions will help to ease the problem.  Smiley Happy

Member
Posts: 8
Registered: ‎25-06-2015

Re: Leg Cramps and Tamoxifen

Hi all.

I tried the magnesium tablets and spray. I take the magnesium phosphate when I can feel a bad bout coming on and it does work eventually.

The magnesium spray is ok but it's very oily so it's putting me off a bit.

The tonic water is due to the quinine in it and it is supposed to help but wasn't doing anything for me. I spoke to my oncologist who prescribed me actual quinine tablets 200 mg to be taken on a night. Apparently you have to be really careful with them as there are some not nice side effects (something else for us to look forward to). They seem to be helping but are giving me bad tummy cramps in the day.

I have now asked my doctor to change my brand of tamoxifen as I honestly think it's worse when I have mylan brand. I've done a week now on the new brand and 3 weeks on quinine and touch wood I've been ok. Although I haven't taken the quinine for a couple of nights due to the tummy pain.

It would be interesting to see if we're all getting different brands if it is related or not.

Good luck everyone. Hope things improve. X
Xx
Member
Posts: 1
Registered: ‎31-10-2017

Re: Leg Cramps and Tamoxifen

I am coming up on two years on Tamoxifen. (Started Jan 1, 2016). I have had horrible arm cramps. But they seemed to have eased up lately so yeah! 

 

I have some tips for those suffering from muscle cramps. I take 800 mg of magnesium a night which I take for constipation but some say it helps with the muscle cramps. Just be sure to start off with a low dosage and work your way up or else be sure you have access to a bathroom. 

 

2) Eat bananas. Potassium helps muscle cramps.

 

3) When you feel a leg cramp coming on, instead of doing what comes naturally and curling your toes outward, curl your toes upwards towards your body. 99 times out of 100, this stops them dead in their tracks. 

Member
Posts: 1
Registered: ‎26-09-2017

Re: Leg Cramps and Tamoxifen

Hello, 

So sorry to hear about your cramping. I empathise. 

I've been on Tamoxifen now for 3 years - and in the past 6 months cramping leg muscles have become an increasing problem. I used to be very sporty and am finding this difficult to deal with. Just wanted to say that prescribed Quinine tablets have stopped the cramping at night but my legs feel heavy and sport options are diminishing. It's hard to know whether this would have happened anyway as I'm menopausal.

 

Try the Quinine perhaps.

 

Best wishes,

 

Clare  

Community Champion
Posts: 9,822
Registered: ‎16-11-2016

Re: Leg Cramps and Tamoxifen

DSLayton

 

I dont know if this will help as it sounds like your cramps are extreme but I have read on here that ladies have been taking a glass of tonic water at bedtime and that seems to have helped them. I would imagine that you have probably tried this, but I thought it might be worth posting to you about it.

 

I sincerely hope that you are able to get this sorted

 

helena xx

Member
Posts: 2
Registered: ‎09-09-2017

Re: Leg Cramps and Tamoxifen

09-09-2017 08:02 PM
I took Tamoxifen for 5 yrs back in the 2000's. Since then I have had terrible cramps in lower legs, ankles, and toes. I have tried every remedy that anyone has posted - with no relief. I went to a Neurologist a couple years ago and he ran every test on me including an EMG and all that were negative. He put me on Gamapentin and Baclofin and the cramps stopped but I was a walking zombie, confused and could not function, so I came off the meds. The cramps are so bad that I asked my medical dr to put me back on Gamapentin and I am starting with 300 mg about 1-2 hrs before bedtime. I have been on it for the last 2 nights and the cramps are really bad. My husband has to get me up and walk me while I shuffle my feet until I can put both feet flat to walk. My blood levels are always perfect. If anyone has any suggestions or info - PLEASE share with me. Thanks
Member
Posts: 2
Registered: ‎09-09-2017

Re: Leg Cramps and Tamoxifen

I took Tamoxifen for 5 yrs back in the 2000's. Since then I have had terrible cramps in lower legs, ankles, and toes. I have tried every remedy that anyone has posted - with no relief. I went to a Neurologist a couple years ago and he ran every test on me including an EMG and all that were negative. He put me on Gamapentin and Baclofin and the cramps stopped but I was a walking zombie, confused and could not function, so I came off the meds. The cramps are so bad that I asked my medical dr to put me back on Gamapentin and I am starting with 300 mg about 1-2 hrs before bedtime. I have been on it for the last 2 nights and the cramps are really bad. My husband has to get me up and walk me while I shuffle my feet until I can put both feet flat to walk. My blood levels are always perfect. If anyone has any suggestions or info - PLEASE share with me. Thanks
Community Champion
Posts: 8,542
Registered: ‎26-10-2015

Re: Leg Cramps and Tamoxifen

Hello. .I take letrozole which is another hormone and find a small glass of tonic water before bed time helps the night cramps ..worth a try. .
Xxx
Member
Posts: 1
Registered: ‎09-08-2017

Re: Leg Cramps and Tamoxifen

I just started Tamoxifen in June. I have wicked lower leg cramps and my toes curl and it's painful! Wakes me up from dead sleep! Then it takes a while to get rid of them and it usually happens at night but sometimes out of nowhere during the day! Also occasionally same thing happens in my hands! Never had this before taking that drug! I'm a nurse. One physician said to take Claritin, calcium and magnesium. I just started that so we will see!
Member
Posts: 8
Registered: ‎25-06-2015

Re: Leg Cramps and Tamoxifen

Out of interest what brand of tamoxifen are you taking at the moment. It's just that I've been monitoring my cramps as I'm the same sometimes I can't walk and I think I've narrowed it down to mylan brand. I also now carry magnesium phosphate tablets as they do really help.
Member
Posts: 1
Registered: ‎21-07-2017

Re: Leg Cramps and Tamoxifen

I am on Tamoxifen since last November. Legs cramps started at the beginning of June. Last night was terrible and i could barely walk this morning!!! I tried to drink tonic water, i take magnesium, calcium, and eat bananas...
Community Champion
Posts: 8,542
Registered: ‎26-10-2015

Re: Leg Cramps and Tamoxifen

Crissy
I'm on another hormone but have you tried a glass of tonic water before bedtime ...it does help the cramps for me.
Xxx
Member
Posts: 2
Registered: ‎15-07-2017

Re: Leg Cramps and Tamoxifen

It's horrible sister xxxx
Member
Posts: 2
Registered: ‎15-07-2017

Re: Leg Cramps and Tamoxifen

I have had leg cramps since I have been talking tamoxifen.. I'm asleep and it wakes me up like now, I am chatting to you and my toes are curling up...so painful
Member
Posts: 3
Registered: ‎23-07-2016

Re: Leg Cramps and Tamoxifen

My Dr. said it takes 30 days for the Tamoxifen to leave your system.    I was on for 5 months, and its been 22 days off.   The severe leg cramps are better, although the ankle, toe cramps are still happening.   I sleep with a heating pad close by, and that relieves the cramping.

Community Champion
Posts: 7,676
Registered: ‎29-05-2015

Re: Leg Cramps and Tamoxifen

It is definitely a side effect of Tamoxifen,I never had these cramps before I started taking it .
Member
Posts: 3
Registered: ‎23-07-2016

Re: Leg Cramps and Tamoxifen

My dr told me also its not from tamoxifen. But it HAS to be from the meds.
Member
Posts: 3
Registered: ‎23-07-2016

Re: Leg Cramps and Tamoxifen

What is the ratio of bicarbonate to water? I have been on tamoxifen for 5 months and can't take the leg and foot cramps. My dr is not convinced it's from tamoxifen.
Member
Posts: 2
Registered: ‎05-03-2016

Re: Leg Cramps and Tamoxifen

I thought I would post an update with my bicarbonate of soda regime and leg cramps.  It is still working, although I have had the odd night (maybe twice a month) when I've woken up with cramp.  I can usually tell when this is going to happen as the cramps start in the early evening.  If that happens I just take the bicarbonate as soon as I feel them starting and also take some bicarb to bed with me and then drink it at night if they start.  It works very quickly.

I've told my doctor what I'm doing and they at least didin't say I shouldn't continue. I was told that one of the common reasons for women wanting to stop tamoxifen treatment was because of leg cramps - certainly I was getting desperate!  

I have altered the time I take my tamoxifen, just in case it shouldn't be taken at the same time as the bicarb.

Anyway the bicarb has revolutionised my sleep and I feel so much better for that!

I hope this is of help.  If anyone else tries it and finds that it works for them, please do post a reply.

 

Member
Posts: 1
Registered: ‎10-05-2016

Re: Leg Cramps and Tamoxifen

I was taking a hot water bottle to bed every night or when I am sitting down watching TV and I found this helped. The last couple of weeks it has been hot and not used water bottle and the cramp came back and I was in tears today. Will certainly try bicarbonate soda or tonic water JackyM