Member
Posts: 677
Registered: ‎03-04-2018

Re: Blood pressure and Letrozole

Hi,

I'very recently started on Letrozole and also have to take the Adcal with it. I've also to have Zometa biphosphonate infusions every 6 months. I've not had a dexa scan so no idea if there's any hint of osteoporosis but was told it's to protect the bones against possible bone met. It's adds a % to your overall survival outcome so it would seem pointless to not have it.
Member
Posts: 257
Registered: ‎13-08-2018

Re: Blood pressure and Letrozole

Hi Patricia,

 

It's good to know you're already taking Vit D and that you'll be speaking to your BC nurse.  

 

It sounds like your oncologist has his own reasons for prescribing the Bis...perhaps he has seen far too often women developing osteoporosis and just wanted to take preventative measures. If I've learned one thing from this forum it is this: consultants are all different and do things differently, and for different reasons. And often there is no "right" or "wrong" about it. They are just all different, as we, women are all differentSmiley Happy.

 

This forum is a really important resource for us all because it arms us with knowledge and info. to take back to our doctors. I don't think I would have had a Dexa bone scan had I not queried it with my oncologist, and I only queried it thanks to this forum and having learned that other women had the scan and that it's a pretty important one to have if on Letrozole.  

 

And re-Helen's concerns about taking one med to counteract the negative effects of the other...I couldn't agree more. But it seems that with cancer, and spefifically BC, the attitude of the healthcare teams is "tough luck". 

 

Though this may be frowned about by traditional medicine....I'm currently listening to podcasts about treating BC naturally...I'm determined to do all I can to avoid surgery. Some of the data is frightening, in particular, the damage that routine screenings can have on cell formation, spread, etc. She also discusses which household products are toxic and contribute to cell growth, and basically says that cancer does not grow in a healthy body-so her ethos is "get healthy". Note: this woman is not a medical doctor but it certainly sounds like she has done her research and I'm trying to be very open-minded about her findings/data.

 

It's a really interesting read/listen. I'm trying to arm myself with as much knowledge as possible... 

 

https://www.audible.co.uk/pd/Heal-Breast-Cancer-Naturally-Audiobook/B00LBIDK66?qid=1545044460&sr=sr_...

 

Please keep us posted on *you*...

xxx

Member
Posts: 135
Registered: ‎09-08-2018

Re: Blood pressure and Letrozole

Hi Patricia _ I was diagnosed in August and had a mastectomy on 24th September. As my 'cancer' was oestrogen positive I was prescribed Letrozole and was also prescribed Vit D/Calcium supplement and was sent for a base line dexa scan.

The dexa scan showed I already had osteoporosis of the lower spine (I had no idea I had it).

My consultant immediately prescribed me with Bisphosphonates - one tablet once a week which has to be taken on the same day/time/empty stomach every week.

I wasn't asked if i wanted them - i was more or less told I needed them.

I don't really like the idea of having to take one medication to counteract the side effects of another one - but hey ho - I just do as i'm told.🤣.

I also had low mood when I first started on the Letrozole - this seems to have lifted now - just feel a bit stiff and achy in my joints - all manageable at the moment.

xxx

Member
Posts: 5
Registered: ‎11-12-2018

Re: Blood pressure and Letrozole

Thanks Marla

I am taking VIT D supplement. Will speak to BN today. Oncologist offered Bis before I had bone Density. He was very clear it was being offered as part of my cancer treatment and not to treat osteoporosis but his words were ghatbis an added bonus. Seeing another oncologist on Thursday as I live in the Isle of Man and Radiotherapy is not available there so having that treatment in Northern Ireland were I am from originally. I will discuss bis with them also.

Take care xxx
Member
Posts: 5
Registered: ‎11-12-2018

Re: Blood pressure and Letrozole

Thank you Helena
Member
Posts: 257
Registered: ‎13-08-2018

Re: Blood pressure and Letrozole

Hi Patricia,

Sorry to hear about your osteopenia and low mood/anxiety.

I, too have osteopenia but my oncologist doesn’t seem to think I need biophos...hence the Vit C/D combo. Perhaps you can ask yours what their thoughts are on the Vit C/D combo for you?

Re-the low mood. I relate very much. I’m just trying to modify my expectations of myself and those of others (of me)...low mood is not fun but I’m willing to tolerate it I’d it means my Letrozole helps. Only time will tell on that front. I’m currently abroad and home late tomorrow but will watch this thread and reply to any other posts from Monday.

Be kind to yourself and explain to your loved ones the effect Letrozole is having on you. That way they will be hopefully be empathic.

xxx
Community Champion
Posts: 9,803
Registered: ‎16-11-2016

Re: Blood pressure and Letrozole

PatriciaMac

 

Hello and welcome to the forum, cant help about the letrozole as although I am post menopausal I am on tamoxifen as I have osteoporosis of the spine.  I am taking a combined Vit D/calcium tablet twice a day and have a Dexa scan every two years. 

 

I am sure someone will come along shortly who might be able to help

 

 

Helena xx

Member
Posts: 5
Registered: ‎11-12-2018

Re: Blood pressure and Letrozole

Hi everyone I am new to the site. Recently diagnosed and had lumpectomy 4 weeks ago. Nodes all clear. On Letrozole coming up on three weeks. Have been offered Bisphosphonates but still decided. Had bone density scan on Thursday. Spine has just dipped into Osteopina. I’m 56. Biggest issue for me is anxiety and very low mood. Any advice gratefully received.
Highlighted
Member
Posts: 257
Registered: ‎13-08-2018

Re: Blood pressure and Letrozole

Hi Paulus,

Thanks very much for your message! I’m pleased to hear you are well-your concoction sounds familiarSmiley Happy I am abroad at the moment without referral letter to hand but the D3 sounds familiar.
xxxx
Member
Posts: 138
Registered: ‎10-08-2018

Re: Blood pressure and Letrozole

Hello Marla

 

I've been on the letrozole since early June, following a May 2018 WLE and axillary clearance - I refused bisphosophonates due to fear/paranoia about the 'small risk' of jaw necrosis ( I don't have good teeth anyway ), and I have Evacal D3 1500mg Chewable Tablets - I think I'm supposed to take 2 a day, but I invariably forget. . . . . .no osteoporosis as yet, but at 63, signs of bone issues. . . . . 

 

Hope you are doing okay Marla x

Member
Posts: 257
Registered: ‎13-08-2018

Re: Blood pressure and Letrozole

Hi Rach1b70,

My sincere apologies for not replying sooner....this was a complete oversight and only now that I logged on today did I notice hadn’t responded.

My BP tends to be on the high side when I’m at the GP but thankfully my home readings are OK.

I’m trying to find my posting on Letrozole and bone density issues (🙄)...can’t find it anywhereSmiley Happy. I ended up having the Dexa bone scan and it revealed early signs of osteopenia (not full blown osteoporosis) and my oncologist wants me to start on a combo Vit C and D tablet, as opposed to the biphosphonates that most women take for osteoporosis. I just wondered whether anyone else had osteopenia as opposed to osteoporosis and what their regime was? I’m very mindful that we are all different and that it isn’t a one size fits all approach.
xxxx
Member
Posts: 110
Registered: ‎17-06-2013

Re: Blood pressure and Letrozole

[ Edited ]

Hi Marla13

 

I know this a little after the original post, but though I would contribute.

 

I am on Letrazole and monthly Zoladex injections. My BP has recently gone through the roof, so they are now monitoring me and have put me on the following meds.

 

6mg Perindopril

10mg Amlodopine

 

I will say, they are still trying to get it lower and the meds seem to keep going up. It has come down a bit, but they would like to see it lower.

 

Not experienced horrendous side effects, so good at the moment.

 

Hope this helps.

 

xxx

Member
Posts: 257
Registered: ‎13-08-2018

Re: Blood pressure and Letrozole

Thanks Sue!

xxxx 

Community Champion
Posts: 1,762
Registered: ‎19-08-2016

Re: Blood pressure and Letrozole

Yes, my oncologist told me not to stop taking the letrozole. It is quite challenging at times, but I will persevere.
Let's hope the gp can find you something else to take. Your BP will need to be down for surgery.
Sue xx
Member
Posts: 257
Registered: ‎13-08-2018

Re: Blood pressure and Letrozole

Thanks a million for your reply Sue! I'm sorry to hear about your BP but I am not surprised from what I've read about Letrozole. I see my GP a week on Monday to discuss whether I need BP meds and if so, which one?  Ramipril didn't suit me but am glad you're OK on it. 

 

At the moment, I'm more concerned about my BP being "OK" for surgery, but the Letrozole interaction is obviously a concern since it sounds like it's a non negotiable for meSmiley Happy. My surgeon is adamant that Letrozole is the best hormone therapy for me, my age, type of cancer, etc.

xxxx

 

Community Champion
Posts: 1,762
Registered: ‎19-08-2016

Re: Blood pressure and Letrozole

Hi Marla
I have been on letrozole for 2 years, and my blood pressure is creeping up. Currently on 10mg of ramipril. I don't have any side effects from it.
I don't know how to help really, but just to confirm that letrozole can affect BP.
Sue xx
Member
Posts: 257
Registered: ‎13-08-2018

Blood pressure and Letrozole

[ Edited ]

Hello lovely ladiesSmiley Happy.

 

I'm getting closer to a surgery date for a L-side mastectomy & DIEP-saw the operating consultant yesterday for the 1st time and she recommends I start on Letrozole (pending my blood tests confirm that I *am* menopausal). However, I've read about the nasty SE's that some of you have experienced on Letrozole, and the one that concerns me most is the possible effect it can have on blood pressure (BP).

 

I am currently *not* taking any BP meds (I *was* on Ramipril for a few months earlier in the year) but negotiated with my GP that I come off it, provided that I take my BP at home (the Ramipril was giving me an awful cough)-I have to speak a lot in my job and the consistent coughing was affecting my ability to do my job, my professionalism, etc. My BP is *not* consistently high, but I do fall into the "hypertension" category; it does spike (average 140-145/85-90) when I am stressed. I was put on Ramipril during a very stressful year and felt confident that once my stress levels reduced, so would my BP-which it did, however, ever since my BC diagnosis 6 weeks ago, my BP readings have started to creep up again. 

 

The BC nurse has advised me to see my GP (soon) to discuss my BP because they won't operate on me if there is a risk that my BP won't be stable throughout the 8 hour operation.

 

So I have two questions:

 

1. For those of you who are on Letrozole...have you noticed an increase in BP? 

2. If yes to #1....are you on BP meds and if so, which one? 

 

I need to discuss an alternative to Ramipril (it just wasn't the right BP med for me given the common SE of a persistent cough) and I would love to hear what meds you are on for BP and how they interact with Letrozole. 

 

Thanks in advance for any input you can provide...

xxx